Kainic Acid-Induced Post-Status Epilepticus Models of Temporal Lobe Epilepsy with Diverging Seizure Phenotype and Neuropathology
The aim of epilepsy models is to investigate disease ontogenesis and therapeutic interventions in a consistent and prospective manner.The kainic acid-induced status epilepticus (KASE) rat model is a widely used, well-validated model for temporal lobe epilepsy (TLE).As we noted significant variability within the model between labs potentially relate